According to Andrej Karpathy (@karpathy), large language models (LLMs) represent a fundamental shift in the software industry, functioning as a new type of computer that can be programmed in plain English. In his recently released AI Startup School talk, Karpathy emphasizes that this paradigm change warrants a major version upgrade for software development, opening up significant business opportunities for startups to leverage natural language programming. The presentation highlights practical applications of LLMs in automating workflows and building AI-driven products, underlining the transformative impact LLMs have on developer productivity and product innovation (Source: @karpathy on Twitter, June 19, 2025).